Eye Can Philippines

Keratoconus Treatment

What is Corneal Cross-Linking?

Corneal cross-linking (CXL) is a minimally invasive outpatient procedure that halts the progression of keratoconus by strengthening the cornea using UV light and riboflavin butyrate.

・Stabilizes the cornea
・Prevents further vision deterioration
・Often avoids the need for corneal transplant
　(About 99% of corneal transplants are due to keratoconus)
・90% success rate in stopping keratoconus progression

Is Cross-Linking Right for You?

It’s best to act early — cross-linking is most
effective when keratoconus is detected soon.

  • Keratoconus

  • Pellucid Marginal
    Degeneration

  • Post-LASIK
    Certain Corneal

  • Corneal Ectasia
    Infections

Why Choose Eye Can?

Non-surgical treatment
Short recovery time
Prevent worsening vision
and stop keratoconus from progressing
Led by experts

Cross-Linking Procedure
（Step-by-Step）

Step 1: Pre-Treatment

• Administer topical anesthesia (eye drops).
• Disinfect around the eyes using a non-alcohol disinfectant.
• Insert a lid speculum to keep the eye open.
• Irrigate the eyes and administer topical anesthesia again.
• Place gauze at the side of the eye to wipe excess fluid.

Step 2: Riboflavin Instillation

• Instill Riboflavin TE eye drops:

・One drop every 30 seconds.
・Use one vial for both eyes.
・Once half the vial is used, change to one drop every 1 minute.


• Soaking time:

・40 minutes if corneal thickness < 400 microns.
・50 minutes if corneal thickness ≥ 400 microns.

Step 3: Pre-Irradiation

• After soaking, irrigate the eyes.
• Administer topical anesthesia again.
• Apply Hyaluronate to keep the cornea moist.

Step 4: UV Irradiation

• Set UV light to 45 mW for 6 minutes.


• Keep 5 cm distance between the cornea and the device.

・(Use a stick with a 5 cm mark to check distance.)


• Use interval mode if available.(more efficient)


• During irradiation:

・Add Hyaluronate as needed.
・Apply anesthesia drops if the patient feels pain.

Step 5: Post-Irradiation

• Place a non-medicated soft contact lens on the eye.
• Let the patient rest for 15 minutes.
• After doctor consultation, patient may go home.

Step 6: Follow-Up

• Soft contact lens:

・Keep on for 3 days.
・At 3-day check-up, remove and check epithelial healing.
・If needed, apply a new lens.


• Monthly check-ups for 6 months:

・Monitor especially intraocular pressure (IOP).
・Charge consultation fee at each visit.

Post-Treatment Medication

First Week (Day 1–7)

• Dexamethasone: 5–6 times/day
• Moxifloxacin: 5–6 times/day
• Hyaluronate: 5–6 times/day

Week 2 to Month 6

• Dexamethasone: 1–2 times/day (switch to FLM if available)
• Hyaluronate: 4 times/day

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